Surgery > Research

Research

Surgeons at UC Irvine have been responsible for many new technologies and therapies to improve healthcare. In fact, UC Irvine is ranked among the top 50 U.S. medical schools for research and primary care, according to U.S. News & World Report rankings.

UC Irvine's Department of Surgery conducts basic research and industry-supported clinical and basic research studies. Committed to remaining at the leading edge of these and many other research efforts, including the exponentially expanding field of cell transplantation, tissue preservation, cell processing and expansion.

We welcome your interest in our research activities and are committed to helping medical students, surgical trainees and young investigators establish mentoring relationships with our faculty. If you are interested in the research activities occurring within our department, please contact Dr. Jeffry Nahmias or Dr. Maheswari Senthil for more infromation.

Basic Science Research Studies

Development of Bio-Artificial Pancreas for Diabetes
Efficacy of Radiation and Sunitinib on Cancer and Stroma in Pancreas Cancer
Enhancing Islet Cell Survival by Inhibiting Apoptosis
The evaluation of enteral protease inhibitor for shock
Hypertonic Resuscitation Following Traumatic Injury
Imaging Pancreatic Islets In-Vivo
The Inflammatory Response to Brain Death

Current Clinical Research Studies

Comparing the safety and efficacy of concentration-controlled Everolimus (Certican,) with low dose Tacolimus (Prograf) to Cellcept ® (mycophenolate mofetil) with standard dose Prograf in de novo renal transplant recipients
The Effect Of Acadesine On Clinically Significant Adverse Cardiovascular and Cerebrovascular Events In High-Risk Subjects Undergoing Coronary Artery Bypass Graft (CABG) Surgery Using Cardiopulmonary Bypass
The Efficacy, Immunogenicity, and Safety of a Single Dose of Merck 0657nI Staphylococcus aureus Vaccine (V710) in Adult Patients Scheduled for Cardiothoracic Surgery
Evaluation of the use of endoscopic stent in management of esophageal leaks after esophagectomy
Compression Anastomosis Ring (CAR 27/Colon Ring) Post Marketing Evaluation Study
Ischemic Conditioning (Delay Phenomenon) in Colorectal Cancer Surgery
Laparoscopic gastric bypass vs. Laparoscopic gastric banding for the treatment of morbid obesity
Observational Long-Term Follow-Up of Living Donors (Kidneys) in an Unique Ethnically Diverse Patient Population
Participation in the American Association for the Surgery of Trauma (AAST) Multi-Center Studies
Participation with the American College of surgeons Bariatric Surgery Center Network studies
Participation in the Research Outcomes Consortium (ROC) Hypertonic Saline for TBI Study
Prospective SICU DVT Prevention Study with an Emphasis on Low Molecular Weight Heparin Dosing
The Relationship Between Parenteral Nutrition, Hyperglycemia and Nosocomial Infections in the SICU
Rabbit Anti-thymocyte Globulin Versus Basiliximab in Deceased Donor Renal Transplants Using a Risk-Adjusted Immunosuppressive Clinical Protocol
Randomized trial of intragastric balloon for the treatment of obesity
Retrospective study of impact of bariatric surgery on improvement or resolution of comorbidities
Retrospective Trauma and Burn Registry Studies
The role of gastric ischemic conditioning in esophagectomy
Timing of Rectal Cancer Response to Chemoradiation. Multi-center Study(COH/NCI)