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Division of Cardiothoracic Surgery

Research

Division faculty members have published numerous articles on the clinical aspects of both thoracic and cardiac surgery, as well as research studies on extended preservation of heart tissues for transplantation.

The division is active in several areas of scientific research, including clinical drug trials and the development of new medical equipment. At UC Irvine’s Chao Family Comprehensive Cancer Center, Division Chief Jeffrey C. Milliken, M.D., serves as principal investigator on clinical trials that explore new treatments for thoracic malignancies.

Other division research projects include:

  • Evaluation of safety and efficacy of modified biologic tissue sealant in cardiac surgery
  • Evaluation of a unique monoclonal antibody inhibiting C5 activation during open heart surgery
  • Evaluation of a vitamin B6 analogue on inflammation and reperfusion injury in open heart surgery
  • Development and testing of a new high-suction vacuum tube drainage system to reduce postoperative bleeding after open heart surgery
  • Safety and efficacy testing of a new cerebral oxygen monitoring system during cardiac surgery
  • Evaluation of somatic muscle transfer in high-risk thoracic surgery
  • Outcomes comparison of percutaneous coronary intervention and coronary bypass surgery in California (with California Society of Thoracic Surgeons)